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A portable colorimetric immunosensor for highly sensitive point-of-care testing of leather artifacts.

Authors :
Zhang C
Li Y
Si H
Du H
Lv L
Xu B
Deng Y
Li J
Yang H
Zhou Y
Wang B
Source :
Mikrochimica acta [Mikrochim Acta] 2024 Nov 27; Vol. 191 (12), pp. 764. Date of Electronic Publication: 2024 Nov 27.
Publication Year :
2024

Abstract

A point-of-care testing (POCT) platform, i.e., a portable colorimetric immunosensor based on iron oxide magnetic beads and AuNPs, has been developed for detecting leather residues. The immunosensor demonstrates a linear detection range from 1 ng/mL to 10 µg/mL, with a limit of detection (LOD) of 0.985 ng/mL. The sensor exhibits high specificity and repeatability and performs effectively in detecting leather artifacts excavated from Inner Mongolia. Thus, the proposed colorimetric immunosensor not only enables the micro-detection of leather artifacts but also shows significant potential for on-site leather detection at archaeological sites.<br />Competing Interests: Declarations. Competing interests: The authors declare no competing interests.<br /> (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)

Details

Language :
English
ISSN :
1436-5073
Volume :
191
Issue :
12
Database :
MEDLINE
Journal :
Mikrochimica acta
Publication Type :
Academic Journal
Accession number :
39601921
Full Text :
https://doi.org/10.1007/s00604-024-06842-y