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Mesenchymal stem cells: Guardians of women's health.

Authors :
Gao G
Li L
Li C
Liu D
Wang Y
Li C
Source :
Regenerative therapy [Regen Ther] 2024 Nov 08; Vol. 26, pp. 1087-1098. Date of Electronic Publication: 2024 Nov 08 (Print Publication: 2024).
Publication Year :
2024

Abstract

Mesenchymal stem cells (MSCs) have attracted more and more attention because of their multidirectional differentiation potential, immune regulatory abilities and self-renewal capacity. In recent years, their use has become prominent in the domains of regenerative medicine and tissue engineering. MSCs have shown promise in therapeutic studies for a variety of diseases and have become a new source of innovative solutions for the treatment of some obstetric and gynecological diseases. This review systematically presents the latest research on the use of MSCs in the treatment of obstetrics- and gynecology-related diseases. Specifically, this review encompasses the latest findings related to the role of MSCs in premature ovarian failure, polycystic ovary syndrome, ovarian cancer, fallopian tube-related diseases, uterine adhesions, endometriosis, cesarean scar defects, postmenopausal osteoporosis, and pelvic floor dysfunction. The shortcomings and challenges of the future use of MSCs in disease treatment are also discussed, with the intent to motivate improvements in MSC applications in clinical therapy. It is believed that with further research, MSCs will play a more important role in the treatment of obstetrics- and gynecology-related diseases.<br />Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (© 2024 The Author(s).)

Details

Language :
English
ISSN :
2352-3204
Volume :
26
Database :
MEDLINE
Journal :
Regenerative therapy
Publication Type :
Academic Journal
Accession number :
39582803
Full Text :
https://doi.org/10.1016/j.reth.2024.10.011