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Mesenchymal stem cells and mesenchymal stem cell-derived exosomes: attractive therapeutic approaches for female reproductive dysfunction.

Authors :
Hassanpour Khodaei S
Sabetkam S
Kalarestaghi H
Dizaji Asl K
Mazloumi Z
Bahramloo M
Norouzi N
Naderali E
Rafat A
Source :
Molecular biology reports [Mol Biol Rep] 2024 Nov 22; Vol. 52 (1), pp. 10. Date of Electronic Publication: 2024 Nov 22.
Publication Year :
2024

Abstract

Infertility is a reproductive health problem in the male or female reproductive system. Traditional assisted reproductive technology (ART) has been unable to solve various cases of infertility for years. Clinical researchers have sought to treat infertility using new methods that are more effective and noninvasive than the old methods. Recently, Mesenchymal stem cells (MSCs) and MSCs-derived Exosomes (MSC-Exos) via paracrine activity play an important role in treating various causes of infertility and improving pregnancy outcomes. In this review, we focus on the roles of MSCs and MSC-Exos cell therapy in female infertility in the different types of female reproductive disorders.<br />Competing Interests: Declarations. Ethics approval: N.A. Consent to participate: N.A. Competing interests: The authors declare no competing interests.<br /> (© 2024. The Author(s), under exclusive licence to Springer Nature B.V.)

Details

Language :
English
ISSN :
1573-4978
Volume :
52
Issue :
1
Database :
MEDLINE
Journal :
Molecular biology reports
Publication Type :
Academic Journal
Accession number :
39576370
Full Text :
https://doi.org/10.1007/s11033-024-10106-6