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Non-coding RNA biosensors for early detection of brain cancer.

Authors :
Karami Y
Ehtiati S
Ghasemi H
Rafiee M
Zamani Sani M
Hosseini SE
Moradi Kazerouni H
Movahedpour A
Aiiashi S
Khatami SH
Source :
Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2025 Jan 30; Vol. 566, pp. 120041. Date of Electronic Publication: 2024 Nov 17.
Publication Year :
2025

Abstract

Brain cancer remains a formidable challenge with limited treatment options. Non-coding RNAs (ncRNAs) have emerged as promising biomarkers due to their dysregulation in tumorigenesis. This review explores the potential of biosensors for early detection of brain cancer by targeting ncRNAs. We discuss the classification and functions of ncRNAs, emphasizing their involvement in key cancer-related processes. Additionally, we delve into recent advancements in biosensor technology, focusing on their ability to accurately detect specific ncRNA biomarkers associated with brain cancer. Our findings underscore the potential of biosensors to revolutionize brain cancer diagnosis, enabling personalized medicine and improving patient outcomes. Future research should focus on refining biosensor technology and expanding their clinical application.<br />Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2024 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1873-3492
Volume :
566
Database :
MEDLINE
Journal :
Clinica chimica acta; international journal of clinical chemistry
Publication Type :
Academic Journal
Accession number :
39561887
Full Text :
https://doi.org/10.1016/j.cca.2024.120041