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Bronchoscopy in children with diffuse alveolar hemorrhage under general anesthesia with spontaneous respiration by face mask ventilation.
- Source :
-
Medicine [Medicine (Baltimore)] 2024 Nov 15; Vol. 103 (46), pp. e40582. - Publication Year :
- 2024
-
Abstract
- To improve the management level of general anesthesia during bronchoscopy in the children with diffuse alveolar hemorrhage (DAH). A retrospective study was conducted in the children with DAH who had performed bronchoscopy under general anesthesia with spontaneous respiration by face mask ventilation initially from June 2021 to June 2022 in our hospital. (1) Thirty-four children who had underwent 38 bronchoscopy procedures were included. (2) General anesthesia induction was performed by bolus of propofol intravenous in all the procedures. For maintaining anesthesia, combination use of propofol and remifentanil intravenously infusion were given in 31 procedures (81.6%) and propofol intravenously infusion alone was given in the rest 7 procedures (18.4%). An intravenous bolus of ketamine or propofol was given as an anesthetic adjuvant in 21 procedures (55.3%). Thirty-five procedures (92.1%) were successfully completed under non-tracheal intubation ventilation, whereas the rest 3 procedures (7.9%) needed change to tracheal intubation ventilation. (3) Respiratory depression was found in 7 procedures (18.4%), laryngospasm was found in 2 procedure (2.6%), and bronchospasm was found in 17 procedures (44.7%). Intraoperative hypoxemia occurred in 16 procedures (42.1%). The incidence of intraoperative hypoxemia in the procedures at the active phage of disease was significantly higher compared to those at the remission phage of the disease (P < .05). Intraoperative hypercapnia also occurred in 16 procedures (42.1%). Two procedures (5.3%) were complicated by severe pulmonary hemorrhage. General anesthesia with spontaneous respiration by face mask ventilation is feasible and relatively safe for the children with DAH undergoing bronchoscopy, whereas the anesthetic protocol still needs to be improved.<br />Competing Interests: The authors have no conflicts of interest to disclose.<br /> (Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.)
- Subjects :
- Humans
Retrospective Studies
Female
Male
Child, Preschool
Child
Infant
Propofol administration & dosage
Propofol adverse effects
Remifentanil administration & dosage
Remifentanil adverse effects
Pulmonary Alveoli
Lung Diseases etiology
Hypoxia etiology
Respiration, Artificial methods
Anesthetics, Intravenous administration & dosage
Anesthetics, Intravenous adverse effects
Ketamine administration & dosage
Masks adverse effects
Anesthesia, General methods
Anesthesia, General adverse effects
Bronchoscopy methods
Bronchoscopy adverse effects
Hemorrhage etiology
Hemorrhage epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1536-5964
- Volume :
- 103
- Issue :
- 46
- Database :
- MEDLINE
- Journal :
- Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 39560565
- Full Text :
- https://doi.org/10.1097/MD.0000000000040582