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Emerging Sialylated Class R Lipooligosaccharides in Campylobacter jejuni from Seagulls Has the Potential to Trigger Guillain-Barré Syndrome - Yunnan Province, China, 2018-2023.

Authors :
Chen X
Gu Y
Wang H
Zhou G
Zhang X
Liu C
Shao Z
Zhang J
Zhang M
Source :
China CDC weekly [China CDC Wkly] 2024 Nov 08; Vol. 6 (45), pp. 1177-1182.
Publication Year :
2024

Abstract

What Is Already Known About This Topic?: Lipooligosaccharides from Campylobacter jejuni ( C. jejuni ) have a mimicry antigen structure with gangliosides, which explains the mechanism by which C. jejuni caused Guillain-Barré syndrome (GBS).<br />What Is Added by This Report?: All 12 C. jejuni strains with class R LOSs and specific serotypes were isolated from seagulls in south China. These emerging C. jejuni strains had ganglioside-mimicry antigen structures and possessed a high potential for triggering GBS.<br />What Are the Implications for Public Health Practice?: Sialylated lipooligosaccharides (LOS) class R with GBS-associated serotypes isolated from seagulls highlight the risk of induced GBS around coastal or lakeside areas.<br />Competing Interests: No conflicts of interest.<br /> (Copyright and License information: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2024.)

Details

Language :
English
ISSN :
2096-7071
Volume :
6
Issue :
45
Database :
MEDLINE
Journal :
China CDC weekly
Publication Type :
Academic Journal
Accession number :
39554219
Full Text :
https://doi.org/10.46234/ccdcw2024.237