Cap-specific m 6 Am modification: A transcriptional anti-terminator by sequestering PCF11 with implications for neuroblastoma therapy.

In this issue of Molecular Cell, An et al. ¹ reports a novel function of cap-specific m ⁶ Am modification acting as an anti-terminator for premature RNA polymerase II transcription by sequestering a transcriptional terminator PCF11. This study provides new insights into RNA modifications in transcriptional control and cancer treatment.
Competing Interests: Declaration of interests The authors declare no competing interests.
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