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[Rehabilitation and outcomes in acquired hemophilia A: a single-center clinical study].

Authors :
Matsumoto A
Ogawa Y
Kajita M
Kobayashi N
Miyazawa Y
Yanagisawa K
Ishizaki T
Tazawa M
Wada N
Souri M
Ichinose A
Handa H
Source :
[Rinsho ketsueki] The Japanese journal of clinical hematology [Rinsho Ketsueki] 2024; Vol. 65 (10), pp. 1270-1275.
Publication Year :
2024

Abstract

The main goals of acquired hemophilia A (AHA) therapy are to arrest bleeding using bypass agents and eradicate FVIII inhibitors using immunosuppressive therapy (IST). We treated a total of 25 patients with AHA in the past 10 years at Gunma University Hospital. Fifteen patients (60%) underwent rehabilitation during hospitalization. The median time from admission to the start of rehabilitation was 31 days (7-142 days). Median FVIII activity at the start of rehabilitation was 11.3% (2.9-79.8%), and median FVIII inhibitor was 2.1 BU/ml (<5.0-46.8 BU/ml). Only one patient (6.7%) had a bleeding event triggered by rehabilitation.

Details

Language :
Japanese
ISSN :
0485-1439
Volume :
65
Issue :
10
Database :
MEDLINE
Journal :
[Rinsho ketsueki] The Japanese journal of clinical hematology
Publication Type :
Academic Journal
Accession number :
39505552
Full Text :
https://doi.org/10.11406/rinketsu.65.1270