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[Ferroptosis:Mechanisms and Application in Tumor Treatment].

Authors :
Shao SH
Qiu ST
Li Y
Zhang YY
Cao YJ
DI CH
Tan XH
Source :
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae [Zhongguo Yi Xue Ke Xue Yuan Xue Bao] 2024 Oct; Vol. 46 (5), pp. 732-739.
Publication Year :
2024

Abstract

Ferroptosis is a form of regulated cell death that depends on iron and reactive oxygen species.Different from apoptosis,necrosis,and autophagy,ferroptosis is characterized by the accumulation of lipid peroxides in cells.Studies have discovered that ferroptosis is closely associated with the occurrence and development of tumors and inducing ferroptosis in tumor cells can enhance the therapeutic effects of drugs on tumors.This article summarizes the latest research progress in ferroptosis regarding its mechanisms and associations with tumors,aiming to provide a reference for further understanding the interaction mechanisms between ferroptosis and tumors and offering new insights and targets for the treatment of tumors.

Details

Language :
Chinese
ISSN :
1000-503X
Volume :
46
Issue :
5
Database :
MEDLINE
Journal :
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
Publication Type :
Academic Journal
Accession number :
39502055
Full Text :
https://doi.org/10.3881/j.issn.1000-503X.15881