First data on tetrodotoxins in Cephalothrix mokievskii (palaeonemertea, nemertea) and possible involvement OF POISONOUS nemerteans in toxification of marine bioresources.

We for the first time have recorded the presence of TTX and 11 of its analogues (TTXs) and determined the profile of these toxins by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) in Cephalothrix mokievskii, collected off the coast of Sakhalin Island and also revealed differences in the TTXs profile between C. mokievskii and sibling Cephalothrix cf, simula. We discuss the features of the TTXs profile in C. mokievskii, geographical distribution of TTX-containing nemerteans and its possible implication for toxification of marine bioresources.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: \Magarlamov T.Yu reports equipment, drugs, or supplies was provided by A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences. Magarlamov T.Yu reports a relationship with A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences that includes: board membership. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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