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[Current status of research on the diagnosis and treatment of acute ethylene glycol poisoning].

Authors :
Yang K
Xiao Kelaiti H
Peng P
Source :
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases [Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi] 2024 Oct 20; Vol. 42 (10), pp. 788-793.
Publication Year :
2024

Abstract

Acute ethylene glycol poisoning often leads to acute kidney injury, and delays in diagnosis and treatment can lead to severe multi-organ dysfunction and even death. At present, there is a lack of specific laboratory tests that can be used for rapid clinical diagnosis, and diagnosis and evaluation only rely on medical history, clinical symptoms, and non-specific laboratory test results. Key treatments include alcohol dehydrogenase inhibitors (fomcpizole or ethanol) and hemodialysis, which is not approved in China. A clear understanding of the mechanism of toxicity, pathophysiology, clinical manifestations, efficacy and limitations of laboratory tests, and treatment options after ethylene glycol poisoning can help accelerate the early diagnosis, treatment, and prognosis of patients after ethylene glycol poisoning. This article reviews this article in order to provide a reference for clinicians.

Details

Language :
Chinese
ISSN :
1001-9391
Volume :
42
Issue :
10
Database :
MEDLINE
Journal :
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
Publication Type :
Academic Journal
Accession number :
39472147
Full Text :
https://doi.org/10.3760/cma.j.cn121094-20231106-00101