An Update on the Fracture Risk Assessment Tool: What Have We Learned over 15+ years?

The Fracture Risk Assessment Tool (FRAX) was launched in 2008 and uses clinical variables to estimate 10-year fracture risk. FRAX has been incorporated into clinical treatment guidelines and is well validated in specific disease states like chronic kidney disease. However, there are risk factors which are not captured by FRAX such as diabetes and falls. The use of race-ethnicity as a factor in FRAX is a source of controversy. Though other risk calculators exist, FRAX is likely to remain the gold standard for fracture risk prediction. An update of FRAX using data from a larger cohort is in development.
Competing Interests: Disclosure R.K. Jain has received research support from the Amgen Foundation, United States in the past and is a past investigator for Radius Pharma. L.T. Dickens has no disclosures.
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