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Clinical Features and Treatment Outcomes of Influenza-Associated Encephalitis and Encephalopathy: A Study on 16 Children in Vietnam.
- Source :
-
Global pediatric health [Glob Pediatr Health] 2024 Oct 11; Vol. 11, pp. 2333794X241286549. Date of Electronic Publication: 2024 Oct 11 (Print Publication: 2024). - Publication Year :
- 2024
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Abstract
- Objectives . This study aims to report clinical features and treatment outcomes of 16 cases diagnosed with post-influenza encephalopathy/encephalitis. Methods . We recorded clinical characteristics of 16 pediatric patients diagnosed with post-influenza encephalopathy/encephalitis at the Vietnam National Children's Hospital from January 2019 to January 2021. Results . There were 87.5% infected with influenza A, with influenza A/H1pdm09 and influenza A/H3 accounting for 88.9% and 11.1% respectively, and 12.5% of participants infected with influenza B. The time from onset to the appearance of neurological symptoms was 3 days, of which perceptual changes (93.8%), hypertonia (75%), and seizures (43.8%) were prevalent neurological symptoms. The majority of cases had normal cerebrospinal fluid. Cranial CT/MRI imaging revealed abnormalities in 87.5% of patients. 56.3% of patients had sequelae, including epilepsy and cerebral palsy; 25% recovered, and 18.8% died after treatment. Conclusions . Influenza-associated encephalitis/encephalopathy is a complication occurring early in children, with high mortality and sequelae rates.<br />Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.<br /> (© The Author(s) 2024.)
Details
- Language :
- English
- ISSN :
- 2333-794X
- Volume :
- 11
- Database :
- MEDLINE
- Journal :
- Global pediatric health
- Publication Type :
- Academic Journal
- Accession number :
- 39421389
- Full Text :
- https://doi.org/10.1177/2333794X241286549