Sustained but Decoyed Activation of the JAK1-STAT Pathway by Aberrant Protein Aggregation Exacerbates Proteotoxicity.

Authors :: Cai M
Pan B
Xiao P
Bouska M
Lewno MT
Xing Y
Zeng E
Liang H
Li F
Gao X
Wang X
Source :: Circulation [Circulation] 2024 Oct 15; Vol. 150 (16), pp. 1302-1305. Date of Electronic Publication: 2024 Oct 14.
Publication Year :: 2024
Abstract: Competing Interests: None.

Subjects :: Humans
Animals
STAT Transcription Factors metabolism
STAT Transcription Factors genetics
Protein Aggregates
Protein Aggregation, Pathological metabolism
Protein Aggregation, Pathological genetics
Mice
Janus Kinase 1 metabolism
Janus Kinase 1 genetics
Signal Transduction

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