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G.3.2 is a novel allele of the gene connector enhancer of ksr ( cnk ) in Drosophila melanogaster .

Authors :
Chammout H
Adkins DL
Al-Olimat AK
Alsaad Z
Altopp BM
Amer T
Apampa FO
Avery GR
Bazzi II
Beck ED
Beier EL
Belisle BS
Benton L
Bolyard MM
Brain OE
Buckner ET
Chowdhury SR
Cifranic JR
Cleary L
Clum TR
Cruz AM
DeGray MV
Echeverry IL
El Dana H
Elkadri SK
Estep PL
Falke LR
Foor HJ
Gullapalli AS
Hakim SS
Hazime HB
Heininger LE
Hoeft EG
James LM
Jeon Y
Johnson MR
Jordan LP
Khan Z
Kochensparger SK
Koria FJ
Krasnow RM
Lilly V
Lim E
MacCormack IT
Malesh A
Mariano MG
Mentzer AC
Messner KH
Myers KC
Newman ER
Richters AM
Romero L
Rotem A
Saho RJ
Sawaki K
Selders AN
Shockney E
Sobh FA
Speiser IF
Sproul BM
Sroufe VJ
Tollkuci A
Trevino CC
Vapenik MA
Wagner EM
Bieser KL
Siders JL
Thackeray JR
Kagey JD
Source :
MicroPublication biology [MicroPubl Biol] 2024 Sep 26; Vol. 2024. Date of Electronic Publication: 2024 Sep 26 (Print Publication: 2024).
Publication Year :
2024

Abstract

Genetic screens in Drosophila melanogaster have long been used to identify genes found in a variety of developmental, cellular, and behavioral processes. Here we describe the characterization and mapping of a mutation identified in a conditional screen for genetic regulators of cell growth and cell division. Within a Flp/FRT system, mutant G.3.2 results in a reduction of mutant tissue and a rough eye phenotype. We find that G.3.2 maps to the gene cnk , providing further support that cnk is a critical gene in Drosophila eye development. This mutant was characterized, mapped and sequenced by undergraduate students within the Fly-CURE consortium.<br />Competing Interests: The authors declare that there are no conflicts of interest present.<br /> (Copyright: © 2024 by the authors.)

Details

Language :
English
ISSN :
2578-9430
Volume :
2024
Database :
MEDLINE
Journal :
MicroPublication biology
Publication Type :
Academic Journal
Accession number :
39399787
Full Text :
https://doi.org/10.17912/micropub.biology.001290