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BODNs as biocompatible brominating reagents: visible-light photocatalytic tyrosine modification under physiologically favorable conditions.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Oct 22; Vol. 60 (85), pp. 12381-12384. Date of Electronic Publication: 2024 Oct 22. - Publication Year :
- 2024
-
Abstract
- The photochemical reactivity of 1-bromo-2-oxo-1,2-dihydronaphthalene-1-carboxylates (BODNs) was demonstrated. They are inert in the dark under physiological conditions but become active as brominating reagents for tyrosine modification under visible light irradiation in the presence of a photocatalyst. The BODNs can be applied to protein labeling with bromo groups as sensitive mass tags.
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 60
- Issue :
- 85
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 39370922
- Full Text :
- https://doi.org/10.1039/d4cc04171b