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Assessment of correlation between lipid ratios and body mass index in patients with type 2 diabetes mellitus in Sarajevo, Bosnia and Herzegovina.
- Source :
-
Endocrine regulations [Endocr Regul] 2024 Oct 01; Vol. 58 (1), pp. 187-194. Date of Electronic Publication: 2024 Oct 01 (Print Publication: 2024). - Publication Year :
- 2024
-
Abstract
- Objective. Studies that have evaluated correlation between body mass index (BMI) and novel lipid indices such as triglycerides (TG)/high-density lipoprotein-cholesterol (HDL-C), total cholesterol (TC)/HDL-C, and low-density lipoprotein cholesterol (LDL-C)/HDL-C in type 2 diabetes mellitus (T2DM) are scarce. Hence, the aim of the present study was to explore the correlation between BMI and novel lipid indices in Bosnian patients with T2DM. Methods. Present study included 117 patients with T2DM (mean age: 66.51 years) and 68 controls (mean age: 68.37 years). BMI was calculated as weight/height². Lipids were measured by standard methods. TG/HDL-C, TC/HDL-C, and LDL-C/HDL-C ratios were separately calculated. The differences between the groups were assessed by Student's t-test or Man Whitney U test. Correlations were determined by Spearman's test. Results. In a total sample of T2DM patients, 41.0% were overweight and 44.4% were obese. In the control group, 51.5% of subjects were overweight and 25.0% were obese. In T2DM group, a significant correlation was observed between BMI and HDL-C, LDL-C, TG/HDL, TC/HDL-C, and LDL-C/HDL-C ratios. In the control group, there was a significant correlation found between BMI and HDL-C, TG, TG/HDL, TC/HDL-C, and LDL-C/HDL-C-ratios. Correlation between BMI and other lipid parameters in T2DM and the control group was not determined. Conclusion. The present study showed significant correlation between BMI and novel lipid indices in both T2DM patients and the control group of subjects. Possible explanation for the observed results might be prevalence of overweight and obese participants in this study sample. Since novel lipid indices are used in the prediction of cardiometabolic risk, results obtained in the present study have valuable clinical implications.<br /> (© 2024 Carla Devantier-Du Plessis et al., published by Sciendo.)
- Subjects :
- Humans
Bosnia and Herzegovina epidemiology
Male
Female
Aged
Middle Aged
Cholesterol, LDL blood
Overweight blood
Overweight epidemiology
Lipids blood
Case-Control Studies
Diabetes Mellitus, Type 2 blood
Diabetes Mellitus, Type 2 epidemiology
Diabetes Mellitus, Type 2 diagnosis
Body Mass Index
Triglycerides blood
Cholesterol, HDL blood
Obesity blood
Obesity epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1336-0329
- Volume :
- 58
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Endocrine regulations
- Publication Type :
- Academic Journal
- Accession number :
- 39352778
- Full Text :
- https://doi.org/10.2478/enr-2024-0022