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Facile construction of benzofulvene frameworks via a palladium-catalysed three-component reaction.
- Source :
-
Organic & biomolecular chemistry [Org Biomol Chem] 2024 Sep 27. Date of Electronic Publication: 2024 Sep 27. - Publication Year :
- 2024
- Publisher :
- Ahead of Print
-
Abstract
- Here we report a three-component reaction of 2-formylarylboronic acids, N -sulfonyl amines and 1,3-enynes, proceeding through a cascade imine formation/Pd <superscript>0</superscript> -catalysed vinylogous addition/intramolecular Suzuki coupling/isomerization process. This protocol exhibited broad substrate scope and good functionality tolerance, and a spectrum of multifunctionalised benzofulvene derivatives were furnished in moderate to good yields and E / Z -selectivity.
Details
- Language :
- English
- ISSN :
- 1477-0539
- Database :
- MEDLINE
- Journal :
- Organic & biomolecular chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 39329403
- Full Text :
- https://doi.org/10.1039/d4ob01414f