Isolated Intraocular Jarisch-Herxheimer Reaction Following Treatment for Syphilitic Chorioretinitis.

A 39-year-old male patient presented with grossly reduced vision in the left eye for the past three months. Fundus evaluation revealed multiple discrete grayish-white deep chorioretinal lesions in the macular area. An optical coherence tomography (OCT) scan in the affected area was normal. Following investigations, a specific diagnosis of syphilitic macular chorioretinitis was made. A repeat OCT on day eight revealed cystic macular edema, consistent with a Jarisch-Herxheimer reaction (JHR). He was started on oral prednisolone in tapering doses and followed up till resolution. The ocular correlates of JHR are rare, and physicians should be aware of the potential of this phenomenon.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Mehta et al.)