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Pretransplant MRD detection of fusion transcripts is strongly prognostic in KMT2A-rearranged acute myeloid leukemia.
- Source :
-
Blood [Blood] 2024 Sep 24. Date of Electronic Publication: 2024 Sep 24. - Publication Year :
- 2024
- Publisher :
- Ahead of Print
-
Abstract
- Pre-transplant detection of KMT2Ar MRD ≥0.001% by quantitative PCR was associated with significantly inferior post-transplant survival (2-year RFS 17% vs 59%; p=0.001) and increased cumulative incidence of relapse (2-year CIR 75% vs 25%, p=0.0004).<br /> (Copyright © 2024 American Society of Hematology.)
Details
- Language :
- English
- ISSN :
- 1528-0020
- Database :
- MEDLINE
- Journal :
- Blood
- Publication Type :
- Academic Journal
- Accession number :
- 39316646
- Full Text :
- https://doi.org/10.1182/blood.2024026605