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Case report: Levodopa challenge test is important in identifying dopamine-induced freezing of gait in patient with Parkinson's disease.

Authors :
Xu SS
Zhu SG
Yuan CX
Zeng GL
Li XT
Liu RP
Huang SS
Zhang X
Wang JY
Source :
Frontiers in human neuroscience [Front Hum Neurosci] 2024 Sep 04; Vol. 18, pp. 1464152. Date of Electronic Publication: 2024 Sep 04 (Print Publication: 2024).
Publication Year :
2024

Abstract

Introduction: Freezing of gait (FOG) is a disabling and heterogeneous symptom in patients with Parkinson's disease (PD). Among them, dopamine-induced FOG is rare and difficult to identify. The treatment of dopamine-induced FOG is complex.<br />Case Presentation: We herein presented a case of PD patient who complicated with refractory FOG. It was identified as dopamine-induced FOG during levodopa challenge test. Her symptoms were alleviated after we reduced the total equivalent dosage of levodopa.<br />Conclusion: Our report emphasizes the importance of levodopa challenge test in identifying different types of FOG, which is very important for further adjusting treatment.<br />Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.<br /> (Copyright © 2024 Xu, Zhu, Yuan, Zeng, Li, Liu, Huang, Zhang and Wang.)

Details

Language :
English
ISSN :
1662-5161
Volume :
18
Database :
MEDLINE
Journal :
Frontiers in human neuroscience
Publication Type :
Academic Journal
Accession number :
39296915
Full Text :
https://doi.org/10.3389/fnhum.2024.1464152