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[Hemorheologic and blood coagulation studies in 94 patients with chronic obstructive peripheral arterial disease].
- Source :
-
La Ricerca in clinica e in laboratorio [Ric Clin Lab] 1985; Vol. 15 Suppl 1, pp. 195-203. - Publication Year :
- 1985
-
Abstract
- During the last three years we have analyzed, in 94 patients with chronic arterial occlusive disease, in order to assess the hemorheological and hemocoagulative balance, the following parameters: prothrombin time, partial thromboplastin time, antithrombin III, antiplasmin, fibrinogen, factor VIII, erythrocyte sedimentation rate, platelet aggregation, erythrocyte filterability and hematocrit values. The main findings were: in 56 patients the hematocrit value was higher than 44%; Katz index was above normal values in 61.7% of the cases; ATIII showed a trend to lower values; platelet aggregation was increased; no significant variations in comparison to normal values were found in FVIII, antiplasmin levels, prothrombin time and partial thromboplastin time. Erythrocyte filterability values were decreased at a level as lower as more advanced was the clinical stage of the disease. These findings show, in agreement with those of other authors, the presence of hyperviscosity and hypercoagulative state in patients with chronic arterial occlusive disease.
- Subjects :
- Aged
Antithrombin III analysis
Chronic Disease
Factor VIII analysis
Female
Fibrinogen analysis
Hematocrit
Humans
Male
Middle Aged
Partial Thromboplastin Time
Platelet Aggregation
Prothrombin Time
alpha-2-Antiplasmin analysis
Arterial Occlusive Diseases physiopathology
Blood Coagulation
Blood Viscosity
Erythrocyte Deformability
Subjects
Details
- Language :
- Italian
- ISSN :
- 0390-5748
- Volume :
- 15 Suppl 1
- Database :
- MEDLINE
- Journal :
- La Ricerca in clinica e in laboratorio
- Publication Type :
- Academic Journal
- Accession number :
- 3929368