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Decoding the diabetic bone paradox: How AGEs sabotage skeletal integrity.

Authors :
Wang J
Cui W
Source :
Cell reports. Medicine [Cell Rep Med] 2024 Sep 17; Vol. 5 (9), pp. 101693.
Publication Year :
2024

Abstract

Diabetes patients often suffer from fractures despite normal or high bone mineral density, a phenomenon known as the diabetic bone paradox. Gao et al. <superscript>1</superscript> identify AGEs as disrupting bone quality and compromising skeletal integrity in diabetic bone disease.<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)

Subjects

Subjects :
Humans
Animals
Fractures, Bone pathology
Diabetes Complications pathology
Diabetes Mellitus pathology
Diabetes Mellitus physiopathology
Bone and Bones pathology
Glycation End Products, Advanced metabolism
Bone Density

Details

Language :
English
ISSN :
2666-3791
Volume :
5
Issue :
9
Database :
MEDLINE
Journal :
Cell reports. Medicine
Publication Type :
Academic Journal
Accession number :
39293394
Full Text :
https://doi.org/10.1016/j.xcrm.2024.101693
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