Got bile? Breastmilk bile acids influence norovirus infection.

Authors :: Baty JJ
Pfeiffer JK
Source :: Cell host & microbe [Cell Host Microbe] 2024 Sep 11; Vol. 32 (9), pp. 1457-1459.
Publication Year :: 2024
Abstract: Breastfeeding provides infection protection for several pathogens but not for noroviruses. Mechanisms explaining this discrepancy have been unclear. In this issue of Cell Host & Microbe, Peiper et al. demonstrate that while breastmilk protects mice from intestinal damage, it promotes neonatal murine norovirus infection due to maternal-derived bile acids. <superscript>1</superscript> .<br />Competing Interests: Declaration of interests J.K.P. is on the advisory board of Cell Host & Microbe.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)