Conversation between host and gut microbiota unveils a "silver bullet" therapeutic option for chemotherapy.

Chemotherapy is associated with the induction of intestinal microbiota dysbiosis and gastrointestinal injuries. In this Cell Host & Microbe issue, Anderson et al. demonstrate that chemotherapy-induced epithelial cell apoptosis drives microbiota imbalance and transcriptional rewiring, which in turn delays intestinal recovery.
Competing Interests: Declaration of interests H.G. holds equity shares in GoldCrest Bio. H.G. is named as an inventor of US Provisional Patent Application Serial No. 62/779,776 entitled “Lachnospiraceae mitigates against radiation-induced hematopoietic/gastrointestinal injury and death, and promotes cancer control by radiation.”
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