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The effectiveness of intravenous zoledronic acid in elderly patients with osteoporosis after rotator cuff repair: a retrospective study.
- Source :
-
Scientific reports [Sci Rep] 2024 Sep 08; Vol. 14 (1), pp. 20891. Date of Electronic Publication: 2024 Sep 08. - Publication Year :
- 2024
-
Abstract
- The aim of this study was to investigate the effect of zoledronic acid (ZA) on postoperative healing and functional rehabilitation in osteoporotic patients with rotator cuff (RC) injury. 96 Patients were divided into three groups according to bone mineral density and ZA use (Group A: normal BMD; Group B: osteoporosis and intravenous ZA use; Group C: osteoporosis, without ZA use). Radiologic, functional and Serological outcomes were evaluated 6 months after surgery. The functional scores in all groups exhibited significant improvement 6 months after surgery. Inter-group comparison showed that Constant Shoulder joint function Score (CSS) of group A not significantly differing from that of group B, the other indicators were significantly better than those of group B and C. There were no significant differences in shoulder forward flexion, abductive Range of Motion between group B and C. Other indicators of group B were significantly improved compared to group C. The retear rate in group C (30.3%, 10/33) was higher than group A (6.1%, 2/33) and group B (13.3%, 4/30). In conclusion, the application of ZA can significantly reduce the rate of RC retear in elderly patients with osteoporosis after surgery, which is significant for postoperative shoulder joint functional rehabilitation.<br /> (© 2024. The Author(s).)
- Subjects :
- Humans
Female
Aged
Male
Retrospective Studies
Range of Motion, Articular drug effects
Treatment Outcome
Middle Aged
Bone Density Conservation Agents administration & dosage
Bone Density Conservation Agents therapeutic use
Aged, 80 and over
Rotator Cuff surgery
Bone Density drug effects
Administration, Intravenous
Zoledronic Acid administration & dosage
Zoledronic Acid therapeutic use
Osteoporosis drug therapy
Rotator Cuff Injuries surgery
Rotator Cuff Injuries drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 2045-2322
- Volume :
- 14
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Scientific reports
- Publication Type :
- Academic Journal
- Accession number :
- 39245701
- Full Text :
- https://doi.org/10.1038/s41598-024-68246-5