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Naso-mucociliary Clearance Time among Patients with Chronic Rhinosinusitis in Ilorin, North-central Nigeria.
- Source :
-
The Nigerian postgraduate medical journal [Niger Postgrad Med J] 2024 Jul 01; Vol. 31 (3), pp. 269-273. Date of Electronic Publication: 2024 Sep 02. - Publication Year :
- 2024
-
Abstract
- Context: The mucociliary clearance system is an important component in the prevention of chronic inflammation of the nasal and paranasal sinus.<br />Aim: The study aims to establish the normal values of mucociliary clearance in our region and to study the variation in mucociliary activity in patients with chronic rhinosinusitis in Ilorin, North-central Nigeria.<br />Settings and Design: This was a prospective, cross-sectional study using consecutive consenting participants in both the control and study groups carried out at both family medicine and otorhinolaryngology clinics among patients attending the clinics.<br />Subjects and Methods: After ethical approval was sought, informed consent was obtained from patients, a modified version of the validated health questionnaire was filled, semi-structured questionnaires were also filled after which patient undergo anterior rhinoscopy, nasal patency test and spirometry was done. The saccharine test has been used to measure nasal-mucociliary clearance time in the past.<br />Statistical Analysis: All information were entered into SPSS version 20 and analysed descriptively, and results were presented in tables and figures.<br />Results: Consecutive consenting 125 patients with rhinosinusitis (study group) and those without rhinosinusitis (control group) underwent naso-mucociliary clearance test. There were 34 males and 91 females with a male:female ratio of 1:2.6 among the study group and 55 males and 70 females with a male:female ratio of 1:1.3 for the control group. The age range was from 18 to 68 years with 18-40 years constituting the modal age group. The mean age for the studied group was 35.7 years while that of the control group was 33.1 years. The mean naso-mucociliary clearance time among the study group was 35.1 min standard deviation (SD = 12.32 ± 1.63), while among the control group, it was 14.8 min (SD = 5.59 ± 0.43).<br />Conclusion: Compared to the control group, there was a roughly 200% prolonged increase in the duration of naso-mucociliary clearance time among patients with rhinosinusitis. There was also a positive correlation with increasing age. Future studies comparing the pre-operative and post-operative treatment of rhinosinusitis will contribute to knowledge.<br /> (Copyright © 2024 Copyright: © 2024 Nigerian Postgraduate Medical Journal.)
Details
- Language :
- English
- ISSN :
- 1117-1936
- Volume :
- 31
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Nigerian postgraduate medical journal
- Publication Type :
- Academic Journal
- Accession number :
- 39219351
- Full Text :
- https://doi.org/10.4103/npmj.npmj_10_24