Back to Search
Start Over
[Clinical Characteristics and Prognosis of Patients with Primary Bone Marrow Lymphoma].
- Source :
-
Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2024 Aug; Vol. 32 (4), pp. 1117-1120. - Publication Year :
- 2024
-
Abstract
- Objective: To investigate the clinical characteristics and prognosis of primary bone marrow lymphoma.<br />Methods: The clinical data of 6 patients with primary bone marrow lymphoma admitted to Gansu Provincial People's Hospital from February 2011 to March 2023 were collected, and their clinical characteristics and prognosis were retrospectively analyzed and summarized.<br />Results: The median age of 6 patients was 61(52-74) years old. There were 2 males and 4 females. All patients had fever and abnormal blood routine examination. Physical examination and imaging examination showed no lymphadenopathy, no extranodal lesions in lung, gastrointestinal, liver and spleen, skin, etc. After strict exclusion of systemic lymphoma involvement in the bone marrow, the diagnosis was confirmed by bone marrow examination, 5 cases were primary myeloid diffuse large B-cell lymphoma and 1 case was primary myeloid peripheral T-cell lymphoma (NOS). 1 case abandoned treatment, 5 cases received CHOP-like or combined R regimen, including 1 case of autologous stem cell transplantation. 4 cases died and 2 case survived. The median OS was 5.5 (1-36) months.<br />Conclusion: The prognosis of primary marrow lymphoma is poor, and bone marrow-related examination is an important means of diagnosis. Diffuse large B-cell lymphoma is the most common histomorphologic and immune subtype, and autologous hematopoietic stem cell transplantation may improve the prognosis.
- Subjects :
- Humans
Male
Female
Prognosis
Middle Aged
Aged
Retrospective Studies
Bone Marrow Neoplasms therapy
Bone Marrow Neoplasms diagnosis
Bone Marrow pathology
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Lymphoma, Large B-Cell, Diffuse diagnosis
Lymphoma, Large B-Cell, Diffuse therapy
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1009-2137
- Volume :
- 32
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Zhongguo shi yan xue ye xue za zhi
- Publication Type :
- Academic Journal
- Accession number :
- 39192407
- Full Text :
- https://doi.org/10.19746/j.cnki.issn.1009-2137.2024.04.022