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Eliater: a Python package for estimating outcomes of perturbations in biomolecular networks.
- Source :
-
Bioinformatics (Oxford, England) [Bioinformatics] 2024 Sep 02; Vol. 40 (9). - Publication Year :
- 2024
-
Abstract
- Summary: We introduce Eliater, a Python package for estimating the effect of perturbation of an upstream molecule on a downstream molecule in a biomolecular network. The estimation takes as input a biomolecular network, observational biomolecular data, and a perturbation of interest, and outputs an estimated quantitative effect of the perturbation. We showcase the functionalities of Eliater in a case study of Escherichia coli transcriptional regulatory network.<br />Availability and Implementation: The code, the documentation, and several case studies are available open source at https://github.com/y0-causal-inference/eliater.<br /> (© The Author(s) 2024. Published by Oxford University Press.)
Details
- Language :
- English
- ISSN :
- 1367-4811
- Volume :
- 40
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Bioinformatics (Oxford, England)
- Publication Type :
- Academic Journal
- Accession number :
- 39187941
- Full Text :
- https://doi.org/10.1093/bioinformatics/btae527