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[Biobanking in clinical trials involving multiple sclerosis patients].

Authors :
Kamenskikh EM
Krygina AY
Gomboeva SC
Zhailebaeva D
Koval DP
Kicherov NA
Otchurzhap CN
Birulina YG
Alifirova VM
Source :
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2024; Vol. 124 (7. Vyp. 2), pp. 7-15.
Publication Year :
2024

Abstract

Investigation of multiple sclerosis (MS) pathogenesis requires sophisticated analytical tools of precision medicine, such as omics research, which include genomics, microbiomics and metabolomics (proteomics, lipidomics and glycomics). Such sensitive methods are based on careful preanalytical work with biomaterials to maintain quality and obtain objective results. Implementation of biobanking as a universal method for working with biomaterials will help to standardize the stages of research, compare different scientific team's results. Collaboration of MS researchers with large biobanks can also help to conduct multicenter and long-term prospective studies, to include a wide number of patients. In this article, we analyze the experience of biobanking practice technologies in studies of MS patients and share the experience of partnership between the Center for MS of the Tomsk Region and the Bank of Biological Material of the Siberian State Medical University.

Details

Language :
Russian
ISSN :
1997-7298
Volume :
124
Issue :
7. Vyp. 2
Database :
MEDLINE
Journal :
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Publication Type :
Review
Accession number :
39175234
Full Text :
https://doi.org/10.17116/jnevro20241240727