Back to Search
Start Over
An investigation of the umbilical artery N-terminal proBrain natriuretic peptide levels of fetuses due to fetal distress in term pregnancies.
- Source :
-
Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2024 Aug 16; Vol. 70 (8), pp. e20240446. Date of Electronic Publication: 2024 Aug 16 (Print Publication: 2024). - Publication Year :
- 2024
-
Abstract
- Objective: This study aimed to investigate umbilical artery N-terminal proBrain natriuretic peptide (NT-proBNP) in fetuses delivered by cesarean section due to fetal distress in term pregnancies.<br />Methods: This prospective case-control study was conducted at the Antalya Training and Research Hospital Obstetric Department, Turkiye. A total of 140 pregnant women, 70 underwent elective cesarean sections between weeks 37 and 40 of gestation (Group 1, the control group) and 70 underwent cesarean sections due to fetal distress (Group 2, the study group), were included. The participants' sociodemographic and obstetric data and fetal umbilical blood NT-proBNP levels were recorded in a database.<br />Results: Age, body mass index, gestational age, prenatal diagnostic tests, fetal anatomical scanning, and baby gender ratios were comparable between the groups (p>0.05), while statistically significant differences were observed in terms of gravidity (3.0 vs. 1.0, p≤0.001) and parity numbers (2 vs. 0, p≤0.001), baby height (50.36±0.88 vs. 49.80±0.86, p≤0.001) and weight (3422.43±409.16 vs. 3239.86±293.74, p=0.003), 1-min Apgar (9.0±0.1 vs. 8.5±1.3, p≤0.001) and 5-min Apgar (10.0±0.1 vs. 9.8±0.4, p=0.026) scores, umbilical artery pH (7.32±0.05 vs. 7.25±0.07, p≤0.001), umbilical artery base deficit (-2.48±1.23 vs. -4.36±1.09. p≤0.001), and NT-proBNP levels [8.77 (7.72-9.39) vs. 12.35 (9.69-12.92), p<0.001].<br />Conclusion: This study showed that NT-proBNP can be used as an important marker in the diagnosis of fetal distress. Prospective studies with more participants are now needed to confirm the accuracy of our results.
- Subjects :
- Humans
Female
Pregnancy
Case-Control Studies
Prospective Studies
Adult
Cesarean Section statistics & numerical data
Gestational Age
Fetal Blood chemistry
Young Adult
Infant, Newborn
Natriuretic Peptide, Brain blood
Umbilical Arteries diagnostic imaging
Fetal Distress blood
Fetal Distress diagnosis
Peptide Fragments blood
Biomarkers blood
Subjects
Details
- Language :
- English
- ISSN :
- 1806-9282
- Volume :
- 70
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Revista da Associacao Medica Brasileira (1992)
- Publication Type :
- Academic Journal
- Accession number :
- 39166684
- Full Text :
- https://doi.org/10.1590/1806-9282.20240446