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A Mystery in a Case: Unraveling the Complexity of Bing-Neel Syndrome.

Authors :
Kotlarz PN
Garcia G
Rosario M
Vargas I
Cai Zhen K
Source :
Cureus [Cureus] 2024 Jul 21; Vol. 16 (7), pp. e65042. Date of Electronic Publication: 2024 Jul 21 (Print Publication: 2024).
Publication Year :
2024

Abstract

Waldenström's macroglobulinemia (WM) is a B-cell non-Hodgkin's lymphoma characterized by clonal IgM-secreting lymphoplasmacytic cell proliferation. Bing-Neel syndrome (BNS) is a rare complication of WM that results in the infiltration of the central nervous system (CNS) with IgM-secreting lymphoplasmacytic cells. This case study presents a 75-year-old Caucasian male with a history of WM and Agent Orange exposure who ultimately was diagnosed with BNS. This patient posed unique diagnostic challenges as the patient experienced clinical symptoms despite the absence of MRI abnormalities and therapeutic challenges.<br />Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.<br /> (Copyright © 2024, Kotlarz et al.)

Details

Language :
English
ISSN :
2168-8184
Volume :
16
Issue :
7
Database :
MEDLINE
Journal :
Cureus
Publication Type :
Academic Journal
Accession number :
39165462
Full Text :
https://doi.org/10.7759/cureus.65042