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Approach to pancytopenia: From blood tests to the bedside.

Authors :
Chew S
Kamangar M
Source :
Clinical medicine (London, England) [Clin Med (Lond)] 2024 Sep; Vol. 24 (5), pp. 100235. Date of Electronic Publication: 2024 Aug 17.
Publication Year :
2024

Abstract

Pancytopenia is an uncommon abnormality detected on a full blood count. Features of presentation tend to be non-specific, and are due to impaired functions of the cell lines involved. These can include fatigue, infection and bleeding. However, the aetiology of pancytopenia is extensive. This narrative review aims to provide a minimally invasive diagnostic algorithm for generalist clinicians to approach pancytopenia, including investigations into the underlying aetiology, and when a referral to the haematologist is warranted for further investigations such as bone marrow aspiration and trephine biopsy.<br />Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)

Details

Language :
English
ISSN :
1473-4893
Volume :
24
Issue :
5
Database :
MEDLINE
Journal :
Clinical medicine (London, England)
Publication Type :
Academic Journal
Accession number :
39159748
Full Text :
https://doi.org/10.1016/j.clinme.2024.100235