From poo to promise: Fecal microbiota transplants support immunotherapy re-sensitization in solid tumors.

Authors :: Chambers L
Grencewicz D
Spakowicz D
Source :: Cell host & microbe [Cell Host Microbe] 2024 Aug 14; Vol. 32 (8), pp. 1217-1218.
Publication Year :: 2024
Abstract: Fecal microbiota transplants (FMTs) recently entered the cancer therapeutics field as a method to resensitize treatment-resistant melanoma patients to immune checkpoint inhibitors (ICIs). In this issue of Cell Host & Microbe, Kim and colleagues extend its utility to other solid tumors, including esophageal and hepatocellular carcinomas. <superscript>1</superscript> .<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2024. Published by Elsevier Inc.)

Subjects :: Humans
Immune Checkpoint Inhibitors therapeutic use
Gastrointestinal Microbiome immunology
Melanoma therapy
Melanoma immunology
Neoplasms therapy
Neoplasms immunology
Esophageal Neoplasms therapy
Esophageal Neoplasms immunology
Esophageal Neoplasms microbiology
Carcinoma, Hepatocellular therapy
Carcinoma, Hepatocellular immunology
Carcinoma, Hepatocellular microbiology
Liver Neoplasms therapy
Liver Neoplasms immunology
Animals
Feces microbiology
Fecal Microbiota Transplantation methods
Immunotherapy methods

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