Chemical synthesis of natural and azido-modified UDP-rhamnose and -arabinofuranose for glycan array-based characterization of plant glycosyltransferases.

Authors :: Pasini I
Ruprecht C
Osswald U
Bittmann A
Maltrovsky L
Romanò C
Clausen MH
Pfrengle F
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Aug 27; Vol. 60 (70), pp. 9368-9371. Date of Electronic Publication: 2024 Aug 27.
Publication Year :: 2024
Abstract: Chemical syntheses of UDP-rhamnose and UDP-arabinofuranose and respective azido-modified analogues are reported. The prepared substrates are useful for the glycan array-based analysis of glycosyltransferases, as exemplified with the plant cell wall-biosynthetic enzymes Pv XAT3, At RRT4 and Pt RRT5.

Subjects :: Azides chemistry
Arabinose chemistry
Arabinose analogs & derivatives
Plants chemistry
Glycosyltransferases metabolism
Glycosyltransferases chemistry
Polysaccharides chemistry
Polysaccharides chemical synthesis
Polysaccharides metabolism
Uridine Diphosphate Sugars chemistry
Uridine Diphosphate Sugars metabolism

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