Central nervous system prophylaxis in large B-cell lymphoma: A British Society for Haematology Good Practice Paper.

Authors :: Wilson MR
Cwynarski K
Eyre TA
Smith J
Chaganti S
Fox CP
McKay P
Source :: British journal of haematology [Br J Haematol] 2024 Aug 11. Date of Electronic Publication: 2024 Aug 11.
Publication Year :: 2024
Publisher :: Ahead of Print
Abstract: This Good Practice Paper provides recommendations for the baseline investigation, risk stratification and use of prophylactic interventions for patients with large B-cell lymphoma at risk of central nervous system relapse. Recent evidence which has questioned the role of high-dose methotrexate in this clinical scenario is discussed in detail.<br /> (© 2024 British Society for Haematology and John Wiley & Sons Ltd.)

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