Biomolecular condensates with liquid properties formed during viral infections.

Authors :: Glon D
Léonardon B
Guillemot A
Albertini A
Lagaudrière-Gesbert C
Gaudin Y
Source :: Microbes and infection [Microbes Infect] 2024 Nov-Dec; Vol. 26 (8), pp. 105402. Date of Electronic Publication: 2024 Aug 08.
Publication Year :: 2024
Abstract: During a viral infection, several membraneless compartments with liquid properties are formed. They can be of viral origin concentrating viral proteins and nucleic acids, and harboring essential stages of the viral cycle, or of cellular origin containing components involved in innate immunity. This is a paradigm shift in our understanding of viral replication and the interaction between viruses and innate cellular immunity.<br />Competing Interests: Conflict of interest The authors declare that they have no conflicts of interest.<br /> (Copyright © 2024 The Authors. Published by Elsevier Masson SAS.. All rights reserved.)