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Adverse social determinants of health elevate uncontrolled hypertension risk: a cardio-oncology prospective cohort study.
- Source :
-
JNCI cancer spectrum [JNCI Cancer Spectr] 2024 Sep 02; Vol. 8 (5). - Publication Year :
- 2024
-
Abstract
- The role of social determinants of health (SDOH) in controlling hypertension (HTN) in cancer patients is unknown. We hypothesize that high SDOH scores correlate with uncontrolled HTN in hypertensive cancer patients. In our prospective study, patients completed the Protocol for Responding to & Assessing Patients' Assets, Risks & Experiences questionnaire. After integrating home and clinic blood pressure readings, uncontrolled HTN was defined as systolic blood pressure greater than or equal to 140 mm Hg and/or diastolic blood pressure greater than or equal to 90 mm Hg. Using Cox regression, we analyzed the impact of SDOH on HTN control, adjusting for relevant factors. The study involved 318 participants (median age 66.4, median follow-up 166 days, SDOH score 6.5 ± 3.2), with stress, educational insecurity, and social isolation as prevalent adverse SDOH. High SDOH scores led to 77% increased risk of uncontrolled HTN (adjusted hazards ratio = 1.77; 95% confidence interval = 1.10 to 2.83, P = .018). Urban residents with high SDOH scores were at an even greater risk. Identifying SDOH and mitigating underlying factors may help control HTN, the most typical disease process treated in all cardio-oncology clinics.<br /> (© The Author(s) 2024. Published by Oxford University Press.)
- Subjects :
- Humans
Prospective Studies
Male
Female
Aged
Middle Aged
Proportional Hazards Models
Stress, Psychological complications
Educational Status
Blood Pressure
Antihypertensive Agents therapeutic use
Antihypertensive Agents adverse effects
Surveys and Questionnaires
Risk Factors
Cardio-Oncology
Hypertension complications
Hypertension drug therapy
Social Determinants of Health
Neoplasms complications
Social Isolation
Subjects
Details
- Language :
- English
- ISSN :
- 2515-5091
- Volume :
- 8
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- JNCI cancer spectrum
- Publication Type :
- Academic Journal
- Accession number :
- 39115393
- Full Text :
- https://doi.org/10.1093/jncics/pkae064