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Complications of new-onset atrial fibrillation in critically ill COVID-19 patients admitted to the intensive care unit (ICU): a meta-analysis.
- Source :
-
BMC cardiovascular disorders [BMC Cardiovasc Disord] 2024 Aug 05; Vol. 24 (1), pp. 407. Date of Electronic Publication: 2024 Aug 05. - Publication Year :
- 2024
-
Abstract
- Background: COVID-19 infections can result in severe acute respiratory distress syndrome (ARDS) requiring admission to the intensive care unit (ICU). Cardiovascular manifestation or exacerbation of cardiovascular diseases could be another complication. Cardiac arrhythmias including New-Onset Atrial Fibrillation (NOAF), have been observed in hospitalized patients with COVID-19 infections. In this analysis, we aimed to systematically compare the complications associated with NOAF in critically ill COVID-19 patients admitted to the ICU.<br />Methods: MEDLINE, EMBASE, Web of Science, the Cochrane database, http://www.<br />Clinicaltrials: gov , Google Scholar and Mendeley were searched for relevant publications based on COVID-19 patients with NOAF admitted to the ICU. Complications including in-hospital mortality, ICU mortality, patients requiring mechanical ventilation, acute myocardial infarction, acute kidney injury, renal replacement therapy and pulmonary embolism were assessed. This is a meta-analysis and the analytical tool which was used was the RevMan software version 5.4. Risk ratios (RR) and 95% confidence intervals (CIs) were used to represent the data post analysis.<br />Results: In critically ill COVID-19 patients with NOAF admitted to the ICU, the risks of ICU mortality (RR: 1.39, 95% CI: 1.07 - 1.80; P = 0.01), in-hospital mortality (RR: 1.56, 95% CI: 1.20 - 2.04; P = 0.001), patients requiring mechanical ventilation (RR: 1.32, 95% CI: 1.04 - 1.66; P = 0.02) were significantly higher when compared to the control group without AF. Acute myocardial infarction (RR: 1.54, 95% CI: 1.31 - 1.81; P = 0.00001), the risk for acute kidney injury (RR: 1.31, 95% CI: 1.11 - 1.55; P = 0.002) and patients requiring renal replacement therapy (RR: 1.83, 95% CI: 1.60 - 2.09; P = 0.00001) were also significantly higher in patients with NOAF.<br />Conclusions: Critically ill COVID-19 patients with NOAF admitted to the ICU were at significantly higher risks of developing complications and death compared to similar patients without AF.<br /> (© 2024. The Author(s).)
- Subjects :
- Humans
Risk Factors
Respiration, Artificial
SARS-CoV-2
Male
Female
Risk Assessment
Middle Aged
Acute Kidney Injury mortality
Acute Kidney Injury therapy
Acute Kidney Injury etiology
Acute Kidney Injury diagnosis
Aged
COVID-19 mortality
COVID-19 complications
COVID-19 therapy
COVID-19 diagnosis
Atrial Fibrillation diagnosis
Atrial Fibrillation mortality
Atrial Fibrillation therapy
Critical Illness
Intensive Care Units
Hospital Mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1471-2261
- Volume :
- 24
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- BMC cardiovascular disorders
- Publication Type :
- Academic Journal
- Accession number :
- 39103764
- Full Text :
- https://doi.org/10.1186/s12872-024-04086-5