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Using a simplified Downes score to predict the receipt of surfactant in a highly resourced setting.

Authors :
Chotas W
Edwards EM
Horn D
Soll R
Ehret DEY
Source :
Journal of perinatology : official journal of the California Perinatal Association [J Perinatol] 2024 Aug 05. Date of Electronic Publication: 2024 Aug 05.
Publication Year :
2024
Publisher :
Ahead of Print

Abstract

Objective: The Downes score is a neonatal examination scoring tool frequently used to guide initiation of CPAP, but its ability to predict the need for surfactant has not been assessed. We assessed the extent to which the Downes score predicts the receipt of surfactant.<br />Study Design: We calculated a simplified Downes score from nursing admission data for infants (≤ 2000 grams, and ≥ 25 weeks' gestation) admitted on CPAP to a highly resourced level III NICU, to assess the predictive value for the receipt of surfactant.<br />Results: Fifty-three (31.5%) out of 168 infants admitted on CPAP received surfactant. A simplified Downes score of ≥ 4 predicted the receipt of surfactant with 90.6% sensitivity, 52.2% specificity, 46.6% positive predictive value, 92.3% negative predictive value, and 64.3% accuracy.<br />Conclusion: The high sensitivity and negative predictive value suggest utility for using the Downes score to help guide clinical decision making regarding surfactant therapy.<br /> (© 2024. The Author(s).)

Details

Language :
English
ISSN :
1476-5543
Database :
MEDLINE
Journal :
Journal of perinatology : official journal of the California Perinatal Association
Publication Type :
Academic Journal
Accession number :
39103471
Full Text :
https://doi.org/10.1038/s41372-024-02086-z