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Prolactinomas: Preconception and During Pregnancy.

Authors :
Zhang CD
Ioachimescu AG
Source :
Endocrinology and metabolism clinics of North America [Endocrinol Metab Clin North Am] 2024 Sep; Vol. 53 (3), pp. 409-419. Date of Electronic Publication: 2024 Jun 18.
Publication Year :
2024

Abstract

Prolactinomas are a common cause of infertility in women. Medical treatment with dopamine agonists (DAs) has an excellent efficacy at restoring fertility and a reassuring safety profile in early pregnancy. Surgical treatment before conception is required in some cases of large macroadenomas and incomplete treatment response. In women with microprolactinomas, the pregnancy course is usually uneventful. In women with macroprolactinomas that are near/abut the optic chiasm, symptomatic tumor enlargement can occur during pregnancy and require a multidisciplinary team approach. This review provides an update regarding outcomes and management of prolactinomas before conception, during pregnancy, and postpartum.<br />Competing Interests: Disclosures The authors have nothing to disclose.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1558-4410
Volume :
53
Issue :
3
Database :
MEDLINE
Journal :
Endocrinology and metabolism clinics of North America
Publication Type :
Academic Journal
Accession number :
39084816
Full Text :
https://doi.org/10.1016/j.ecl.2024.05.004