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Prolactinomas: Preconception and During Pregnancy.
- Source :
-
Endocrinology and metabolism clinics of North America [Endocrinol Metab Clin North Am] 2024 Sep; Vol. 53 (3), pp. 409-419. Date of Electronic Publication: 2024 Jun 18. - Publication Year :
- 2024
-
Abstract
- Prolactinomas are a common cause of infertility in women. Medical treatment with dopamine agonists (DAs) has an excellent efficacy at restoring fertility and a reassuring safety profile in early pregnancy. Surgical treatment before conception is required in some cases of large macroadenomas and incomplete treatment response. In women with microprolactinomas, the pregnancy course is usually uneventful. In women with macroprolactinomas that are near/abut the optic chiasm, symptomatic tumor enlargement can occur during pregnancy and require a multidisciplinary team approach. This review provides an update regarding outcomes and management of prolactinomas before conception, during pregnancy, and postpartum.<br />Competing Interests: Disclosures The authors have nothing to disclose.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
Pregnancy
Female
Dopamine Agonists therapeutic use
Dopamine Agonists adverse effects
Preconception Care methods
Prolactinoma therapy
Prolactinoma drug therapy
Pituitary Neoplasms therapy
Pituitary Neoplasms complications
Pregnancy Complications, Neoplastic therapy
Pregnancy Complications, Neoplastic drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1558-4410
- Volume :
- 53
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Endocrinology and metabolism clinics of North America
- Publication Type :
- Academic Journal
- Accession number :
- 39084816
- Full Text :
- https://doi.org/10.1016/j.ecl.2024.05.004