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Intensified Circulation of Echovirus 11 after the COVID-19 Pandemic in Poland: Detection of a Highly Pathogenic Virus Variant.
- Source :
-
Viruses [Viruses] 2024 Jun 24; Vol. 16 (7). Date of Electronic Publication: 2024 Jun 24. - Publication Year :
- 2024
-
Abstract
- After the first phase of the COVID-19 pandemic in Europe, a new highly pathogenic variant of echovirus 11 (E11) was detected. The aim of this study was to analyze the genetic diversity of Polish E11 environmental and clinical strains circulating between 2017 and 2023 as well as compare them with E11 strains isolated from severe neonatal sepsis cases reported in Europe between 2022 and 2023. Additionally, the study explores the effectiveness of environmental monitoring in tracking the spread of new variants. For this purpose, the complete sequences of the VP1 capsid protein gene were determined for 266 E11 strains isolated in Poland from 2017 to 2023, and phylogenetic analysis was performed. In the years 2017-2023, a significant increase in the detection of E11 strains was observed in both environmental and clinical samples in Poland. The Polish E11 strains represented three different genotypes, C3, D5 and E, and were characterized by a high diversity. In Poland, the intensive circulation of the new variant E11, responsible for severe neonatal infections with a high mortality in Europe, was detected in the years 2022-2023. This investigation demonstrates the important role of environmental surveillance in the tracking of enteroviruses circulation, especially in settings with limited clinical surveillance.
- Subjects :
- Poland epidemiology
Humans
Genotype
Genetic Variation
Capsid Proteins genetics
Infant, Newborn
Echovirus Infections epidemiology
Echovirus Infections virology
Pandemics
Phylogeny
Enterovirus B, Human genetics
Enterovirus B, Human classification
Enterovirus B, Human isolation & purification
COVID-19 epidemiology
COVID-19 virology
SARS-CoV-2 genetics
SARS-CoV-2 classification
SARS-CoV-2 isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1999-4915
- Volume :
- 16
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Viruses
- Publication Type :
- Academic Journal
- Accession number :
- 39066174
- Full Text :
- https://doi.org/10.3390/v16071011