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Clinical impact of MRI on indeterminate findings on contrast-enhanced CT suspicious of HCC.
- Source :
-
Scandinavian journal of gastroenterology [Scand J Gastroenterol] 2024 Sep; Vol. 59 (9), pp. 1075-1080. Date of Electronic Publication: 2024 Jul 26. - Publication Year :
- 2024
-
Abstract
- Objectives: In patients evaluated for hepatocellular carcinoma (HCC), magnetic resonance imaging (MRI) is often used secondarily when multiphase contrast-enhanced computed tomography (ceCT) is inconclusive. We investigated the clinical impact of adding MRI.<br />Materials and Methods: This single-institution retrospective study included 48 MRI scans (44 patients) conducted from May 2016 to July 2023 due to suspicion of HCC on a multiphase ceCT scan. Data included medical history, preceding and subsequent imaging, histology when available, and decisions made at multidisciplinary team meetings.<br />Results: In case of possible HCC recurrence, 63% of the MRI scans were diagnostic of HCC. For 80% of the negative MRI scans, the patients were diagnosed with HCC within a median of 165 days in the suspicious area of the liver. In case of possible de-novo HCC in patients with cirrhosis, 22% of the scans were diagnostic of HCC and 33% of the negative MRI scans were of patients diagnosed with HCC within a median of 109 days. None of the non-cirrhotic patients with possible de-novo HCC and negative MRI scans (64%) were later diagnosed with HCC, but 3/5 of the indeterminate scans were of patients diagnosed with HCC in a biopsy.<br />Conclusions: Secondary MRI to a multiphase ceCT scan suspicious of HCC is highly valuable in ruling out HCC in non-cirrhotic patients and in diagnosing HCC non-invasively in cirrhotic patients and patients with prior HCC. Patients with cirrhosis or prior HCC are still at high risk of having HCC if MRI results are inconclusive or negative.
- Subjects :
- Humans
Retrospective Studies
Male
Female
Aged
Middle Aged
Liver Cirrhosis diagnostic imaging
Neoplasm Recurrence, Local diagnostic imaging
Aged, 80 and over
Liver diagnostic imaging
Liver pathology
Adult
Carcinoma, Hepatocellular diagnostic imaging
Carcinoma, Hepatocellular pathology
Liver Neoplasms diagnostic imaging
Liver Neoplasms pathology
Magnetic Resonance Imaging
Tomography, X-Ray Computed
Contrast Media
Subjects
Details
- Language :
- English
- ISSN :
- 1502-7708
- Volume :
- 59
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Scandinavian journal of gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 39061129
- Full Text :
- https://doi.org/10.1080/00365521.2024.2384952