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Beyond conventional therapies: IVIG in treating severe fingolimod-rebound in a postpartum patient with MS.
- Source :
-
BMJ case reports [BMJ Case Rep] 2024 Jul 25; Vol. 17 (7). Date of Electronic Publication: 2024 Jul 25. - Publication Year :
- 2024
-
Abstract
- This case report details a female patient with multiple sclerosis in her 30s, who experienced a significant fingolimod rebound syndrome post partum, characterised by worsening neurological symptoms and severe demyelinating lesions. Traditional treatments, including steroids and plasmapheresis, were ineffective. However, the introduction of intravenous immunoglobulin (IVIG) led to remarkable improvement in her symptoms and disability status. This case highlights the complex immunological changes associated with fingolimod cessation and underscores IVIG's potential as a valuable treatment in managing such rebounds.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Limited 2024. No commercial re-use. See rights and permissions. Published by BMJ.)
Details
- Language :
- English
- ISSN :
- 1757-790X
- Volume :
- 17
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- BMJ case reports
- Publication Type :
- Academic Journal
- Accession number :
- 39059796
- Full Text :
- https://doi.org/10.1136/bcr-2024-259932