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Use of Split-Thickness Skin Grafts and Autologous Skin Cell Suspension in a Case of Extensive Fournier Gangrene.

Authors :
English CJ
Sodade OE
Austin CL
Causa KA
Source :
Cureus [Cureus] 2024 Jun 18; Vol. 16 (6), pp. e62639. Date of Electronic Publication: 2024 Jun 18 (Print Publication: 2024).
Publication Year :
2024

Abstract

Fournier gangrene (FG) is a life-threatening necrotizing soft-tissue infection of the perineum and external genitalia, which primarily occurs in obese, diabetic males. The mainstay of treatment is source control via early aggressive surgical excision. Wide surgical excision can result in significant soft tissue defects that can be disfiguring and difficult to close. The most common method of closure is split-thickness skin grafting (STSG). Recently, autologous skin cell suspension (ASCS) technology has been used in addition to STSG to provide better wound healing and closure. This patient experienced excellent wound progression, following FG, through the application of ASCS with STSG, despite challenges related to the wounds, anatomical location, comorbidities, size, and the patient's medical history.<br />Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.<br /> (Copyright © 2024, English et al.)

Details

Language :
English
ISSN :
2168-8184
Volume :
16
Issue :
6
Database :
MEDLINE
Journal :
Cureus
Publication Type :
Academic Journal
Accession number :
39036212
Full Text :
https://doi.org/10.7759/cureus.62639