Back to Search Start Over

LeishGEM: genome-wide deletion mutant fitness and protein localisations in Leishmania.

Source :
Trends in parasitology [Trends Parasitol] 2024 Aug; Vol. 40 (8), pp. 675-678. Date of Electronic Publication: 2024 Jul 18.
Publication Year :
2024

Abstract

LeishGEM is a genome-wide functional annotation community resource for Leishmania mexicana, where deletion mutant growth in vitro and in vivo is measured and protein localisation is determined by endogenous tagging and LOPIT-DC (localisation of organelle proteins by isotope tagging with differential centrifugation) spatial proteomics. Data are being made available pre-publication via http://leishgem.org which allows data-driven identification of the mechanisms for Leishmania parasitism.<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)

Details

Language :
English
ISSN :
1471-5007
Volume :
40
Issue :
8
Database :
MEDLINE
Journal :
Trends in parasitology
Publication Type :
Academic Journal
Accession number :
39030136
Full Text :
https://doi.org/10.1016/j.pt.2024.06.003