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LeishGEM: genome-wide deletion mutant fitness and protein localisations in Leishmania.
- Source :
-
Trends in parasitology [Trends Parasitol] 2024 Aug; Vol. 40 (8), pp. 675-678. Date of Electronic Publication: 2024 Jul 18. - Publication Year :
- 2024
-
Abstract
- LeishGEM is a genome-wide functional annotation community resource for Leishmania mexicana, where deletion mutant growth in vitro and in vivo is measured and protein localisation is determined by endogenous tagging and LOPIT-DC (localisation of organelle proteins by isotope tagging with differential centrifugation) spatial proteomics. Data are being made available pre-publication via http://leishgem.org which allows data-driven identification of the mechanisms for Leishmania parasitism.<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1471-5007
- Volume :
- 40
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Trends in parasitology
- Publication Type :
- Academic Journal
- Accession number :
- 39030136
- Full Text :
- https://doi.org/10.1016/j.pt.2024.06.003