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Additive and Dominance Genome-Wide Association Studies Reveal the Genetic Basis of Heterosis Related to Growth Traits of Duhua Hybrid Pigs.

Authors :
Qiao J
Li K
Miao N
Xu F
Han P
Dai X
Abdelkarim OF
Zhu M
Zhao Y
Source :
Animals : an open access journal from MDPI [Animals (Basel)] 2024 Jun 30; Vol. 14 (13). Date of Electronic Publication: 2024 Jun 30.
Publication Year :
2024

Abstract

Heterosis has been extensively used for pig genetic breeding and production, but the genetic basis of heterosis remains largely elusive. Crossbreeding between commercial and native breeds provides a good model to parse the genetic basis of heterosis. This study uses Duhua hybrid pigs, a crossbreed of Duroc and Liangguang small spotted pigs, as materials to explore the genetic basis underlying heterosis related to growth traits at the genomic level. The mid-parent heterosis (MPH) analysis showed heterosis of this Duhua offspring on growth traits. In this study, we examined the impact of additive and dominance effects on 100 AGE (age adjusted to 100 kg) and 100 BF (backfat thickness adjusted to 100 kg) of Duhua hybrid pigs. Meanwhile, we successfully identified SNPs associated with growth traits through both additive and dominance GWASs (genome-wide association studies). These findings will facilitate the subsequent in-depth studies of heterosis in the growth traits of Duhua pigs.

Details

Language :
English
ISSN :
2076-2615
Volume :
14
Issue :
13
Database :
MEDLINE
Journal :
Animals : an open access journal from MDPI
Publication Type :
Academic Journal
Accession number :
38998055
Full Text :
https://doi.org/10.3390/ani14131944