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Activity-induced reactivity of astrocytes impairs cognition.

Activity-induced reactivity of astrocytes impairs cognition.

Authors :
Bohmbach K
Henneberger C
Source :
PLoS biology [PLoS Biol] 2024 Jul 12; Vol. 22 (7), pp. e3002712. Date of Electronic Publication: 2024 Jul 12 (Print Publication: 2024).
Publication Year :
2024

Abstract

Glial cells such as astrocytes can modulate neuronal signaling. Astrocytes can also acquire a reactive phenotype that correlates with cognitive impairments in brain diseases. A study in PLOS Biology shows that prolonged activation of astrocytes can trigger both cognitive impairments and a reactive astrocyte phenotype.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright: © 2024 Bohmbach, Henneberger. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Details

Language :
English
ISSN :
1545-7885
Volume :
22
Issue :
7
Database :
MEDLINE
Journal :
PLoS biology
Publication Type :
Academic Journal
Accession number :
38996200
Full Text :
https://doi.org/10.1371/journal.pbio.3002712