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Hepatic amyloidosis in a patient with chronic liver failure: A case report.

Authors :
Chen Y
Peng J
Wang Y
Xiao LH
Liu F
Wei YB
Wu XF
Wang LW
Source :
World journal of clinical cases [World J Clin Cases] 2024 Jul 06; Vol. 12 (19), pp. 3918-3924.
Publication Year :
2024

Abstract

Background: Amyloidosis is a rare disorder that can be classified into various types, and the most common type is the systemic light chain type. The prognosis of this disease is extremely poor. In general, amyloidosis mainly affects the kidneys and heart and manifests as abnormal proliferation of clonal plasma cells. Cases in which the liver is the primary organ affected by amyloidosis, as in this report, are less common in clinical practice.<br />Case Summary: A 62-year-old man was admitted with persistent liver dysfunction of unknown cause and poor treatment outcomes. His condition persisted, and he developed chronic liver failure, with severe cholestasis in the later stage that was gradually accompanied by renal injury. Ultimately, he was diagnosed with hepatic amyloidosis through liver biopsy and pathological examination.<br />Conclusion: Hepatic amyloidosis rarely occurs in the clinic, and liver biopsy and pathological examination can assist in the accurate and effective diagnosis of this condition.<br />Competing Interests: Conflict-of-interest statement: All authors declare that they have no conflicts of interest.<br /> (©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.)

Details

Language :
English
ISSN :
2307-8960
Volume :
12
Issue :
19
Database :
MEDLINE
Journal :
World journal of clinical cases
Publication Type :
Academic Journal
Accession number :
38994313
Full Text :
https://doi.org/10.12998/wjcc.v12.i19.3918