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Connecting the dots: Computational network analysis for disease insight and drug repurposing.

Authors :
Siminea N
Czeizler E
Popescu VB
Petre I
Păun A
Source :
Current opinion in structural biology [Curr Opin Struct Biol] 2024 Oct; Vol. 88, pp. 102881. Date of Electronic Publication: 2024 Jul 10.
Publication Year :
2024

Abstract

Network biology is a powerful framework for studying the structure, function, and dynamics of biological systems, offering insights into the balance between health and disease states. The field is seeing rapid progress in all of its aspects: data availability, network synthesis, network analytics, and impactful applications in medicine and drug development. We review the most recent and significant results in network biomedicine, with a focus on the latest data, analytics, software resources, and applications in medicine. We also discuss what in our view are the likely directions of impactful development over the next few years.<br />Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)

Details

Language :
English
ISSN :
1879-033X
Volume :
88
Database :
MEDLINE
Journal :
Current opinion in structural biology
Publication Type :
Academic Journal
Accession number :
38991238
Full Text :
https://doi.org/10.1016/j.sbi.2024.102881